靶标：
Kin
产品别名：
Kin17； Kin； Kin17 DNA and RNA binding protein； Kin17 DNA and RNA binding protein； DNA/RNA-binding protein KIN17； KIN, antigenic determinant of recA protein homolog； antigenic determinant of rec-A protein； binding to curved DNA；
背景信息：
DNA/RNA-binding protein KIN17, also known as BTCD or KIN17 is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.
