靶标:
Nkx2-6
产品别名:
AV044928; Nkx-2.6; Nkx2.6; Tix; tinman; Nkx2-6; NK2 homeobox 6; NK2 homeobox 6; homeobox protein Nkx-2.6; Drosophila NK2 transcription factor related, locus 6; NK2 transcription factor related, locus 6; homeobox protein NK-2 homolog F; 转录因子同源蛋白Nkx2.6;
背景信息:
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011],