靶标:
Plcb1
产品别名:
3110043I21Rik; AI132408; Plcb; mKIAA0581; Plcb1; phospholipase C, beta 1; phospholipase C, beta 1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; PLC-154; PLC-beta-1; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-1; phospholipase C-beta-1a; 磷脂酰肌醇特异性磷酯酶Cβ1(PLCB1); 磷酯酶Cβ1;
背景信息:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],