靶标:
Bpifa1
产品别名:
LUNX; NASG; Plunc; SPLUNC1; SPURT; Bpifa1; BPI fold containing family A, member 1; BPI fold containing family A, member 1; BPI fold-containing family A member 1; palate lung and nasal epithelium clone protein; palate, lung, and nasal epithelium associated; palate, lung, and nasal epithelium clone; palate, lung, and nasal epithelium expressed transcript; protein Plunc; 腭/肺/鼻上皮癌关联蛋白(PLUNC);
背景信息:
This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014],