靶标:
Pola2
产品别名:
AI573378; Pola2; polymerase (DNA directed), alpha 2; polymerase (DNA directed), alpha 2; DNA polymerase alpha subunit B; DNA polymerase alpha 2, 68 kDa; DNA polymerase alpha 70 kDa subunit; DNA聚合酶α2;
背景信息:
domain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,