靶标：
Ptf1a
产品别名：
PTF1-p48； PTF1p48； bHLHa29； Ptf1a； pancreas specific transcription factor, 1a； pancreas specific transcription factor, 1a； pancreas transcription factor 1 subunit alpha； bHLH transcription factor p48； p48 DNA-binding subunit of transcription factor PTF1； pancreas transcription factor1 p48 subunit； 胰腺特异转录因子1α(PTF1a)； 胰腺特异转录因子PTF1A；
背景信息：
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008],
