靶标:
Slc22a12
产品别名:
AI987855; OAT4L; Rst; Slc22al2; URAT1; Slc22a12; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 member 12; renal-specific transporter; solute carrier family 22 (organic cation transporter)-like 2; urate anion exchanger 1; 尿酸盐转运蛋白1(URAT1); 尿酸盐重吸收转运子1;
背景信息:
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],