靶标:
Prap1
产品别名:
Upa; Prap1; proline-rich acidic protein 1; proline-rich acidic protein 1; proline-rich acidic protein 1; pregnancy-specific uterine protein; uterine-specific proline-rich acidic protein;
背景信息:
Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids and MTTP-mediated apoB lipoprotein assembly and secretion (By similarity. Protects the gastrointestinal epithelium from irradiation-induced apoptosis (By similarity. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May downregulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas.