靶标:
CASC3
产品别名:
BTZ; MLN51; CASC3; CASC3 exon junction complex subunit; CASC3 exon junction complex subunit; protein CASC3; MLN 51; barentsz; cancer susceptibility 3; cancer susceptibility candidate 3; cancer susceptibility candidate gene 3 protein; metastatic lymph node 51; metastatic lymph node gene 51 protein; protein barentsz; 肿瘤易感候选基因3;
背景信息:
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008],