靶标:
CNKSR2
产品别名:
CNK2; KSR2; MAGUIN; MRXSHG; CNKSR2; connector enhancer of kinase suppressor of Ras 2; connector enhancer of kinase suppressor of Ras 2; connector enhancer of kinase suppressor of ras 2; CNK homolog protein 2; connector enhancer of KSR2; membrane-associated guanylate kinase-interacting protein; Ras激酶抑制因子连接增强蛋白2;
背景信息:
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],