靶标:
FAN1
产品别名:
KIAA1018; KMIN; MTMR15; hFAN1; FAN1; FANCD2 and FANCI associated nuclease 1; FANCD2 and FANCI associated nuclease 1; fanconi-associated nuclease 1; FANCD2/FANCI-associated nuclease 1; coiled-coil domain-containing protein MTMR15; fanconi anemia associated nuclease 1; myotubularin-related protein 15; 范可尼综合征相关蛋白FAN1;
背景信息:
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],