靶标:
TRIM32
产品别名:
BBS11; HT2A; LGMD2H; LGMDR8; TATIP; TRIM32; tripartite motif containing 32; tripartite motif containing 32; E3 ubiquitin-protein ligase TRIM32; 72 kDa Tat-interacting protein; RING-type E3 ubiquitin transferase TRIM32; TAT-interactive protein, 72-KD; tripartite motif-containing protein 32; zinc-finger protein HT2A; 神经干细胞抑制相关蛋白TRIM32;
背景信息:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.