靶标：
WDFY3
产品别名：
ALFY； BCHS； MCPH18； ZFYVE25； WDFY3； WD repeat and FYVE domain containing 3； WD repeat and FYVE domain containing 3； WD repeat and FYVE domain-containing protein 3； autophagy-linked FYVE protein； WDFY3蛋白；
背景信息：
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
