靶标:
UBR2
产品别名:
C6orf133; bA49A4.1; dJ242G1.1; dJ392M17.3; UBR2; ubiquitin protein ligase E3 component n-recognin 2; ubiquitin protein ligase E3 component n-recognin 2; E3 ubiquitin-protein ligase UBR2; RING-type E3 ubiquitin transferase UBR2; ubiquitin-protein ligase E3-alpha-2; ubiquitin-protein ligase E3-alpha-II; 泛素蛋白连接酶E3α2;
背景信息:
This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],