靶标：
ITGB3BP
产品别名：
CENP-R； CENPR； HSU37139； NRIF3； TAP20； ITGB3BP； integrin subunit beta 3 binding protein； integrin subunit beta 3 binding protein； centromere protein R； beta 3 endonexin； beta3-endonexin； integrin beta 3 binding protein (beta3-endonexin)； integrin beta-3-binding protein； nuclear receptor-interacting factor 3；
背景信息：
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011],
