靶标:
GPR161
产品别名:
RE2; GPR161; G protein-coupled receptor 161; G protein-coupled receptor 161; G-protein coupled receptor 161; G-protein coupled receptor RE2; G蛋白偶联受体GPR161蛋白;
背景信息:
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008],