靶标:
POFUT1
产品别名:
DDD2; FUT12; O-FUT; O-Fuc-T; O-FucT-1; OFUCT1; POFUT1; protein O-fucosyltransferase 1; protein O-fucosyltransferase 1; GDP-fucose protein O-fucosyltransferase 1; o-fucosyltransferase protein; peptide-O-fucosyltransferase 1; 蛋白O-岩藻糖基转移酶1(POFUT1); 蛋白O岩藻糖基转移酶1;
背景信息:
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],