靶标:
MAPK8IP2
产品别名:
IB-2; IB2; JIP2; PRKM8IPL; MAPK8IP2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; C-Jun-amino-terminal kinase-interacting protein 2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; homologous to mouse JIP-1; islet-brain 2; 丝裂原活化蛋白激酶相互作用蛋白2;
背景信息:
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. [provided by RefSeq, Feb 2014],