靶标：
SMUG1
产品别名：
FDG； HMUDG； UNG3； SMUG1； single-strand-selective monofunctional uracil-DNA glycosylase 1； single-strand-selective monofunctional uracil-DNA glycosylase 1； single-strand selective monofunctional uracil DNA glycosylase； SMUG1蛋白； 单链选择性单功能尿嘧啶DNA糖基化酶1(SMUG1)；
背景信息：
The base excision repair (BER) pathway corrects small base lesions in DNA due to oxidation, deamination, or misincorporation of dUTP instead of dTTP during DNA replication. These bases are removed by DNA glycosylases, resulting in abasic sites that are then repaired through short- or long-patch BER (1,2).
Single-strand-selective monofunctional uracil-DNA glycosylase 1 (SMUG1) removes uracil and oxidized pyrimidines from DNA. SMUG1 expression is important for genome stability, and high expression of SMUG1 is correlated with favorable prognosis in human cancer (3). Knockdown or knockout of SMUG1 results in decreased proliferation, as well as increased DNA damage and apoptosis (4).
宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
