靶标：
FLRT2
产品别名：
FLRT2； fibronectin leucine rich transmembrane protein 2； fibronectin leucine rich transmembrane protein 2； leucine-rich repeat transmembrane protein FLRT2； fibronectin-like domain-containing leucine-rich transmembrane protein 2； 富含亮氨酸跨膜纤连蛋白2； 纤连蛋白亮氨酸丰富跨膜蛋白2(FLRT2)；
背景信息：
fibronectin leucine rich transmembrane protein 2(FLRT2) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
