靶标:
BRD1
产品别名:
BRL; BRPF1; BRPF2; BRD1; bromodomain containing 1; bromodomain containing 1; bromodomain-containing protein 1; BR140-like protein; bromodomain and PHD finger-containing protein 2; BRD1蛋白; 含溴区蛋白1(BRD1);
背景信息:
This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],