靶标:
Pappa2
产品别名:
PAPP-A2; PLAC3; Pappe; Pappa2; pappalysin 2; pappalysin 2; pappalysin-2; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; pregnancy-associated plasma protein-E; 妊娠相关血浆蛋白A2; 妊娠相关血浆蛋白A2(PAPPA2);
背景信息:
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010],