靶标：
Spry4
产品别名：
A030006O18Rik； sprouty4； Spry4； sprouty RTK signaling antagonist 4； sprouty RTK signaling antagonist 4； protein sprouty homolog 4； 快速发育生长因子同源蛋白4；
背景信息：
This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014],
