靶标：
ABI3BP
产品别名：
NESHBP； TARSH； ABI3BP； ABI family member 3 binding protein； ABI family member 3 binding protein； target of Nesh-SH3； ABI family, member 3 (NESH) binding protein； ABI gene family member 3-binding protein； ABI gene family, member 3 (NESH) binding protein； nesh-binding protein； ABI基因家族成员3结合蛋白；
背景信息：
A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.
