靶标:
KANK2
产品别名:
ANKRD25; MXRA3; NPHS16; PPKWH; SIP; KANK2; KN motif and ankyrin repeat domains 2; KN motif and ankyrin repeat domains 2; KN motif and ankyrin repeat domain-containing protein 2; SRC-interacting protein; SRC1-interacting protein; ankyrin repeat domain-containing protein 25; kidney ankyrin repeat-containing protein 2; matrix-remodeling-associated protein 3;
背景信息:
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016],