靶标：
FBXL5
产品别名：
FBL4； FBL5； FLR1； FBXL5； F-box and leucine rich repeat protein 5； F-box and leucine rich repeat protein 5； F-box/LRR-repeat protein 5； F-box protein FBL4/FBL5； p45SKP2-like protein； FBXL5蛋白；
背景信息：
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010],
