靶标:
MYCBP
产品别名:
AMY-1; MYCBP; MYC binding protein; MYC binding protein; C-Myc-binding protein; associate of myc-1; c-myc binding protein; C myc结合蛋白; C-Myc结合蛋白(MYCBP);
背景信息:
The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011],