靶标:
GNL3
产品别名:
C77032; E2IG3; NNP47; NS; GNL3; G protein nucleolar 3; G protein nucleolar 3; guanine nucleotide-binding protein-like 3; E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide binding protein-like 3 (nucleolar); novel nucleolar protein 47; nucleolar GTP-binding protein 3; nucleostemin; 核干细胞因子鸟嘌呤核苷酸结合蛋白3;
背景信息:
可能是维持干细胞的增殖能力所需要。稳定MDM2通过防止其泛素化,从而蛋白酶体降解。