靶标:
ELP4
产品别名:
AN; AN2; C11orf19; PAX6NEB; PAXNEB; dJ68P15A.1; hELP4; ELP4; elongator acetyltransferase complex subunit 4; elongator acetyltransferase complex subunit 4; elongator complex protein 4; PAX6 neighbor gene protein; elongation protein 4 homolog; ELP4蛋白;
背景信息:
This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants.