靶标:
Cops4
产品别名:
AW208976; D5Ertd774e; SGN4; Cops4; COP9 signalosome subunit 4; COP9 signalosome subunit 4; COP9 signalosome complex subunit 4; COP9 (constitutive photomorphogenic) homolog, subunit 4; COP9 (constitutive photomorphogenic), subunit 4; COP9 complex S4; JAB1-containing signalosome subunit 4; signalosome subunit 4; 信号转导蛋白亚基4;
背景信息:
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.