靶标:
PPA2
产品别名:
HSPC124; SCFAI; SCFI; SID6-306; PPA2; inorganic pyrophosphatase 2; inorganic pyrophosphatase 2; inorganic pyrophosphatase 2, mitochondrial; PPase 2; pyrophosphatase (inorganic) 2; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2;
背景信息:
Inorganic pyrophosphatase 2, mitochondrial is is a protein that in humans is encoded by the PPA2 gene. It is mapped to 4q24. The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.