靶标:
DKK3
产品别名:
CRRL; REIC; RIG; DKK3; dickkopf WNT signaling pathway inhibitor 3; dickkopf WNT signaling pathway inhibitor 3; dickkopf-related protein 3; RIG-like 5-6; RIG-like 7-1; cardiomyocyte regeneration-related lncRNA; dickkopf 3 homolog; dickkopf homolog 3; dickkopf-3; dkk-3; hDkk-3; regulated in glioma; Dickkopf相关蛋白3(DKK3); 抑癌蛋白DKK3;
背景信息:
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],