靶标:
AFF4
产品别名:
AF5Q31; CHOPS; MCEF; AFF4; ALF transcription elongation factor 4; ALF transcription elongation factor 4; AF4/FMR2 family member 4; ALL1-fused gene from chromosome 5q31 protein; major CDK9 elongation factor-associated protein; 淋巴细胞相关AF4样蛋白;
背景信息:
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011],