靶标:
DISC1
产品别名:
C1orf136; SCZD9; DISC1; DISC1 scaffold protein; DISC1 scaffold protein; disrupted in schizophrenia 1 protein; DISC1 C端; DISC1 N端; 精神分裂症破坏蛋白1(DISC1);
背景信息:
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],