靶标:
GPR78
产品别名:
GPR78; G protein-coupled receptor 78; G protein-coupled receptor 78; G-protein coupled receptor 78; G蛋白偶联受体78; G蛋白偶联受体78(GPR78); G蛋白偶联受体GPR78蛋白;
背景信息:
The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011],