靶标：
TUBGCP4
产品别名：
76P； GCP-4； GCP4； Grip76； MCCRP3； TUBGCP4； tubulin gamma complex associated protein 4； tubulin gamma complex associated protein 4； gamma-tubulin complex component 4； gamma tubulin ring complex protein (76p gene)； gamma-ring complex protein 76 kDa； γ-微管蛋白GCP4；
背景信息：
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],
