靶标：
LSM1
产品别名：
CASM； YJL124C； LSM1； LSM1 homolog, mRNA degradation associated； LSM1 homolog, mRNA degradation associated； U6 snRNA-associated Sm-like protein LSm1； LSM1 homolog, U6 small nuclear RNA associated； LSM1 mRNA degradation associated； LSM1, U6 small nuclear RNA associated； LSM1-like protein U6 small nuclear RNA associated； cancer-associated Sm protein； cancer-associated Sm-like protein； small nuclear ribonuclear CaSm； LSM1蛋白；
背景信息：
LSM1 homolog, mRNA degradation associated(LSM1) Homo sapiens This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011],
