靶标:
PDLIM3
产品别名:
ALP; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; alpha-actinin-2-associated LIM protein; enigma homolog; 辅肌动蛋白相关LIM蛋白;
背景信息:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],