靶标:
TNRC6A
产品别名:
CAGH26; FAME6; GW1; GW182; TNRC6; TNRC6A; trinucleotide repeat containing adaptor 6A; trinucleotide repeat containing adaptor 6A; trinucleotide repeat-containing gene 6A protein; CAG repeat protein 26; CTD-2540M10.1; EDIE; EMSY interactor protein; GW182 autoantigen; glycine-tryptophan protein of 182 kDa; trinucleotide repeat containing 6A; GW182蛋白; 含三核苷酸重复序列蛋白6A(TNRC6A);
背景信息:
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.