靶标:
POLM
产品别名:
Pol Mu; Tdt-N; POLM; DNA polymerase mu; DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; Pol iota; polymerase (DNA) mu; polymerase (DNA-directed), mu; terminal transferase; DNA聚合酶μ/DNA polμ;
背景信息:
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,