靶标：
NOB1
产品别名：
ART-4； MST158； MSTP158； NOB1P； PSMD8BP1； NOB1； NIN1 (RPN12) binding protein 1 homolog； NIN1 (RPN12) binding protein 1 homolog； RNA-binding protein NOB1； NIN1/PSMD8 binding protein 1 homolog； PSMD8 binding protein 1； adenocarcinoma antigen recognized by T lymphocytes 4； nin one binding protein； phosphorylation regulatory protein HP-10； protein ART-4； RNA结合蛋白NOB1；
背景信息：
RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene. In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.
