靶标：
COMMD5
产品别名：
HCARG； HT002； COMMD5； COMM domain containing 5； COMM domain containing 5； COMM domain-containing protein 5； hypertension-related calcium-regulated gene protein；
背景信息：
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity. Down-regulates activation of NF-kappa-B.
