靶标:
USP25
产品别名:
USP21; USP25; ubiquitin specific peptidase 25; ubiquitin specific peptidase 25; ubiquitin carboxyl-terminal hydrolase 25; USP on chromosome 21; deubiquitinating enzyme 25; ubiquitin thioesterase 25; ubiquitin thiolesterase 25; ubiquitin-specific processing protease 25;
背景信息:
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008],