靶标:
OSGIN1
产品别名:
BDGI; OKL38; OSGIN1; oxidative stress induced growth inhibitor 1; oxidative stress induced growth inhibitor 1; oxidative stress-induced growth inhibitor 1; BMSC-derived growth inhibitor; bone marrow stromal cell-derived growth inhibitor; ovary, kidney and liver protein 38; pregnancy-induced growth inhibitor OKL38; 氧化应激诱导生长抑制因子1; 氧化应激诱导生长抑制因子1(OSGIN1);
背景信息:
This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011],