靶标：
EFEMP2
产品别名：
ARCL1B； FBLN4； MBP1； UPH1； EFEMP2； EGF containing fibulin extracellular matrix protein 2； EGF containing fibulin extracellular matrix protein 2； EGF-containing fibulin-like extracellular matrix protein 2； EGF containing fibulin like extracellular matrix protein 2； FIBL-4； fibulin 4； mutant p53 binding protein 1； 纤连蛋白4； 衰老关键蛋白4(FBLN4)；
背景信息：
A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011],
