靶标：
KCNIP3
产品别名：
CSEN； DREAM； KCHIP3； KCNIP3； potassium voltage-gated channel interacting protein 3； potassium voltage-gated channel interacting protein 3； calsenilin； A-type potassium channel modulatory protein 3； DRE-antagonist modulator； Kv channel interacting protein 3, calsenilin； calsenilin, presenilin-binding protein, EF hand transcription factor； kv channel-interacting protein 3； potassium channel interacting protein 3； Kv通道相互作用蛋白3(KCNIP3)； 钾通道相互作用蛋白3；
背景信息：
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
