靶标:
KCNIP1
产品别名:
KCHIP1; VABP; KCNIP1; potassium voltage-gated channel interacting protein 1; potassium voltage-gated channel interacting protein 1; Kv channel-interacting protein 1; A-type potassium channel modulatory protein 1; Kv channel interacting protein 1; potassium channel interacting protein 1; vesicle APC-binding protein; A型钾离子通道调节蛋白1;
背景信息:
This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],