靶标:
Usp47
产品别名:
BcDNA:LD12764; CG5486; D-UBP-64E; D-Ubp-64E; Dmel\CG5486; E(var)1; E(var)3-64E; E-var(3)64E; Q24574; UBP; UBP64E; Ubp64; Ubp64E; Upd64E; dUSP47; dUbp64; ubp64; ubp64E; usp47; Usp47; Ubiquitin specific protease 47; Ubiquitin specific protease 47; ubiquitin specific protease 47; CG5486-PA; CG5486-PB; CG5486-PD; Ubiquitin-specific protease 64E; Usp47-PA; Usp47-PB; Usp47-PD;
背景信息:
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB, stabilizing POLB thereby playing a role in base-excision repair (BER. Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.