靶标:
Atg10
产品别名:
ATG10; CG12821; Dmel\CG12821; Atg10; Autophagy-related 10; Autophagy-related 10; Autophagy-related 10; Atg10-PB; Atg10-PD; Autophagy-specific gene 10; CG12821-PB; CG12821-PD; 自噬相关蛋白10;
背景信息:
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008],