靶标：
Nox4
产品别名：
AI648021； Nox4； NADPH oxidase 4； NADPH oxidase 4； NADPH oxidase 4； KOX-1； kidney oxidase-1； kidney superoxide-producing NADPH oxidase； renal NAD(P)H-oxidase； superoxide-generating NADPH oxidase 4； NADPH氧化酶4； NADPH氧化酶NOX家族的成员4； 尼克酰胺腺嘌呤二核苷酸磷酸氧化酶4(NOX4)；
背景信息：
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],
